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R J Dempsey Selected Research

N-Methyl-D-Aspartate Receptors (NMDA Receptors)

8/2001Neuroprotection by memantine, a non-competitive NMDA receptor antagonist after traumatic brain injury in rats.
8/2000Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats.

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R J Dempsey Research Topics

Disease

9Brain Ischemia (Cerebral Ischemia)
01/2002 - 03/2000
7Traumatic Brain Injuries (Traumatic Brain Injury)
10/2001 - 01/2000
7Ischemia
10/2001 - 03/2000
4Stroke (Strokes)
01/2005 - 01/2000
4Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2003 - 03/2001
3Brain Injuries (Brain Injury)
05/2006 - 01/2000
3Transient Ischemic Attack
01/2002 - 08/2001
3Infarction (Infarctions)
06/2001 - 03/2000
3Brain Edema (Cerebral Edema)
08/2000 - 01/2000
2Wounds and Injuries (Trauma)
03/2000 - 03/2000
1Prostatic Neoplasms (Prostate Cancer)
03/2013
1Neoplasms (Cancer)
03/2013
1Bipolar Disorder (Manic Depressive Psychosis)
05/2006
1Niemann-Pick Diseases (Niemann Pick Disease)
05/2006
1Nervous System Diseases (Neurological Disorders)
05/2006
1Schizophrenia (Dementia Praecox)
05/2006
1Neurodegenerative Diseases (Neurodegenerative Disease)
05/2006
1Cerebral Infarction
01/2003
1Inflammation (Inflammations)
11/2001
1Ischemic Stroke
01/2001
1Edema (Dropsy)
03/2000
1Craniocerebral Trauma (Head Injury)
01/2000

Drug/Important Bio-Agent (IBA)

5Cytidine Diphosphate Choline (Citicoline)IBA
01/2002 - 03/2000
2LipidsIBA
05/2006 - 12/2000
2Messenger RNA (mRNA)IBA
01/2003 - 03/2000
2Phospholipases (Phospholipase)IBA
01/2002 - 03/2001
2SphingomyelinsIBA
01/2002 - 12/2000
2Phospholipids (Phosphatides)FDA LinkGeneric
10/2001 - 12/2000
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
08/2001 - 08/2000
2GABA-A Receptors (GABA(A) Receptor)IBA
06/2001 - 01/2000
2Glutamic Acid (Glutamate)FDA Link
05/2001 - 03/2001
2Amino Acid Transport System X-AG (Glutamate Transporter)IBA
03/2001 - 05/2000
2Cardiolipins (Cardiolipin)IBA
03/2001 - 12/2000
2salicylhydroxamic acid (SHAM)IBA
03/2001 - 03/2000
2Phosphatidylinositols (Phosphatidylinositol)IBA
03/2001 - 12/2000
1LigandsIBA
03/2013
1Ethanol (Ethyl Alcohol)IBA
03/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2013
1Neurotransmitter Agents (Neurotransmitter)IBA
11/2001
1Glutathione Reductase (Glutathione-Disulfide Reductase)IBA
10/2001
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
10/2001
1Glutathione (Reduced Glutathione)IBA
10/2001
1Memantine (Namenda)FDA Link
08/2001
1Antisense OligonucleotidesIBA
08/2001
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
08/2001
1NeurosteroidsIBA
06/2001
1Bumetanide (Bumex)FDA LinkGeneric
06/2001
1PK 11195 (PK11195)IBA
06/2001
1Sodium-Potassium-Chloride SymportersIBA
06/2001
1OligodeoxyribonucleotidesIBA
03/2001
1TransferasesIBA
03/2001
1Oxygen (Dioxygen)IBA
03/2001
1Phosphatidylcholines (Phosphatidylcholine)IBA
03/2001
1EnzymesIBA
03/2001
1SpermineIBA
03/2001
1Glucose (Dextrose)FDA LinkGeneric
03/2001
1SpermidineIBA
03/2001
1phosphatidylethanolamineIBA
12/2000
1CeramidesIBA
12/2000
1Arachidonic Acid (Vitamin F)IBA
12/2000
1PhosphatidylserinesIBA
12/2000
11-aminoindan-1,5-dicarboxylic acidIBA
10/2000
1Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
10/2000
1pyridineIBA
10/2000
1ifenprodilIBA
08/2000
1PolyaminesIBA
08/2000
1Indicators and Reagents (Reagents)IBA
08/2000
1MDL 72527IBA
03/2000
1Fluorescein (Funduscein)FDA LinkGeneric
03/2000
1Polyamine OxidaseIBA
03/2000
1Coloring Agents (Dyes)IBA
03/2000
1Evans Blue (Blue, Evans)FDA Link
03/2000
16- chloro- 3,5- diaminopyrazine- 3- carboxamideIBA
03/2000
1Neuroprotective AgentsIBA
03/2000
1PutrescineIBA
03/2000
1triphenyltetrazoliumIBA
01/2000
1Protective AgentsIBA
01/2000

Therapy/Procedure

2Therapeutics
01/2005 - 01/2001
2Operative Surgical Procedures
03/2000 - 01/2000
1Heterologous Transplantation (Xenotransplantation)
03/2013
1Euthanasia (Mercy Killing)
10/2001
1Aftercare (After-Treatment)
03/2000